Bio F1B

Bio 14.6

Bio TO-2

Bio F1D

Bio NT

Bio HT

Bio 87.20

Bio 15.16

Bio 1.5

Bio Golden Syrian

Bio F1D
Description
The Bio F1D hybrid hamsters is a genetically-defined hamster, derived from 2 highly carcenogen-susceptable inbred hamster strains (Bio 15.16 male x Bio 87.20 female) they have a long lifespan, no spontaneous tumors and a dose response related tumor incidence, with known carcinogen.
Applications

Carcinogenicity testing



References


F. Homburger, R. A. Adams, P. Bernfeld, C. G. VanDongen, and E. Soto. A New First-Generation Hybrid Syrian hamster, BIO F1D Alexander for in vivo Carcinogenesis Bioassay, as a third species or to replace the mouse. Tissue Cell 1:125-133, 1983.
F. Homburger. Background data on tumor incidence in control animals (Syrian hamsters). Prog.Exp.Tumor Res. 26:259-265, 1983.
F. Homburger, C. G. Van Dongen, R. A. Adams, and E. Soto. Standardizing Syrian Hamsters for Toxicology. Safety Evaluation and Regulation of Chemicals:225-232, 1983.
P. Bernfeld, F. Homburger, R. A. Adams, E. Soto, and C. G. Van Dongen. Base-line data in a carcinogen-susceptible first-generation hybrid strain of Syrian golden hamsters: F1D Alexander. J.Natl.Cancer Inst. 77 (1):165-171, 1986.
W. G. Hammond, R. L. Teplitz, and J. R. Benfield. A step section method for full histopathological assessment of carcinogen-affected target tissue during respiratory carcinogenesis 1. Microsc.Res Tech. 26 (5):466-471, 1993
R. W. Sawyer, W. G. Hammond, R. L. Teplitz, and J. R. Benfield. Regression of bronchial epithelial cancer in hamsters 1 147. Ann.Thorac.Surg. 56 (1):74-78, 1993.