Bio F1B

Bio 14.6

Bio TO-2

Bio F1D

Bio NT

Bio HT

Bio 87.20

Bio 15.16

Bio 1.5

Bio Golden Syrian

Bio To-2
 Description

This is a genetically defined mutant Syrian hamster, (Sole reference).  This mutation affects all muscle systems namely smooth muscle, skeletal muscle and cardiac muscle.

Applications

  • Cardiomyopathy
  • Muscular dystrophy
  • Arrhythmia
  • Heart failure
  • Rend disease
  • Gene therapy
  • Gait abnormalities
  • ECG abnormalities

 
Selected References

1. Gertz, 1972. Cardiomyopathic Syrian Hamster...
2. Homburger, 1979. Myopathy of Hamster Dystrophy....
3. Sole, 1986. Hamster Cardiomyopathy: Understanding...
4. Nigro, 1997. Identification of the Syrian hamster cardiomyopathy gene.
5. Sakamoto, 1997. Both hypertrophic and dilated cardiomyopathies...
6. Xiao, 2000. Full functional rescue of a complete muscle....
7. Kawada, 2002. Rescue of hereditary form of dilated....
8. Zsu, 2005. Sustained Whole-Body functional rescue in....
9. Wang, 2005, Adeno-associated virus serotype 8 efficiently....
10. Dieterle, 2005. Gene transfer of a phospholamban-targeted....
11. AJP- Heart 289:2409-2415,2005. First published Jul 15, 2005;doi:10.1152/ajpheart.00483.2005
Additional Reference List