Tag: antibody myc
TMPRSS2 usage by SARS-CoV-2 Omicron impacts tropism and fusogenicity
- Benjamin
- 0
Here we show that Omicron spike has higher affinity for ACE2 compared to Delta as well as a marked change of antigenicity conferring significant evasion of therapeutic monoclonal and vaccine-elicited polyclonal neutralising antibodies after two doses. mRNA vaccination as a third vaccine dose rescues and broadens neutralization.Importantly, antiviral drugs remdesivir and molnupiravir retain efficacy against Omicron BA.1.…
Read Moregenomic analyses of Polymyxin-resistant Enterobacteriaceae strains from China
- Benjamin
- 0
Background: This has brought great challenges to the treatment of multidrug-resistant Escherichia coli and K. pneumoniae. Results: K. pneumoniae 16BU137 and E. coli 17MR471 were isolated from the bus and subway handrails in Guangzhou, China. K. pneumoniae 19PDR22 and KP20191015 were isolated from patients with urinary tract infection and severe pneumonia in Anhui, China. The mcr-1.1…
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