covid 19 Diagnosis test series

covid 19 Diagnosis test series

CDC has developed two laboratory tests that identify SARS-CoV-2, the virus that causes COVID-19. The first test for COVID-19 diagnosis that CDC distributed, released in February 2020, is the CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel, a test that accurately detects SARS-CoV-2 in respiratory specimens. CDC released a second assay in July 2020, the CDC Influenza SARS-CoV-2 (Flu SC2) Multiplex Assay, which permits public health laboratories to run three tests in a single reaction well. The Flu SC2 Multiplex is more efficient in its use of test reagents, allows higher throughput, and simultaneously gives accurate results about the presence of SARS-CoV-2, influenza A, and influenza B nucleic acid in a patient specimen. Symptoms for COVID-19 and the Flu can be similar, so testing for all three viruses at the same time will provide public health officials with information they need to help reduce the spread of these viruses in the community while conserving resources that are in short supply.

Please note: CDC will discontinue the CDC 2019-nCoV Real-time RT-PCR Diagnostic Panel at the end of 2021. For more details, please see the CDC 2019-nCoV Real-time RT-PCR Diagnostic Panel section below.

Introduction

Compared to 2002/2003 SARS-CoV and 2012–2014 MERS-CoV epidemics, COVID-19 coronavirus rapidly spread to other parts of the world (185 countries and territories, Last updated: March 21, 2020)().

In symptomatic patients, the clinical manifestations of the disease usually start after less than a week, consisting of fever (body temperature 37 to 38°C), cough, nasal congestion, and fatigue (). Pneumonia mostly occurs in the second or third week of a symptomatic infection (). Comparison of hematological parameters between mild and severe cases of COVID-19 showed significant differences in interleukin-6 (IL-6), D-Dimer, glucose (GLU), thrombin time (TT), fibrinogen (FIB) and C-reactive protein (CRP) (). Fan et al. analyzed the hematological indices of COVID‐19 infected patients between the intensive care unit (ICU) and non‐ICU patients. They showed lymphopenia and raised lactate dehydrogenase (LDH) were associated with higher rate of ICU admissions. Patients who were transferred to the ICU had a lower nadir lymphocyte count, nadir monocyte count and nadir hemoglobin, and higher peak Neutrophil (NEU) Count and peak LDH levels compared to patients who did not require ICU stay () . Many patients with MERS-CoV had liver function abnormalities with elevated alanine aminotransferase (ALT), aspartate aminotransferase (AST), and LDH (). Also laboratory data on SARS have shown that most patients had elevated CRP levels, lymphopenia, leukopenia, and elevated levels of aminotransferase, LDH and creatine kinase (). A series of recently published articles have reported the epidemiological and clinical characteristics of patients with COVID-19 disease, but data regarding the laboratory characteristics of infected individuals are limited (). This study aimed to evaluate the accuracy of laboratory parameters in predicting cases with positive RT-PCR for COVID-19.

covid 19 Diagnosis test series
    covid 19 Diagnosis test series

Methods

Study design and setting

This diagnostic accuracy study was conducted on suspected COVID-19 patients, who presented to Behpooyan Clinic Medical center in Tehran (Iran) from 22 February to 14 March, 2020. Patients were divided into two groups based on the results of real time reverse transcriptase‐polymerase chain reaction (RT-PCR) for COVID-19 and the accuracy of different laboratory parameters in predicting cases with positive RT-PCR was evaluated using area under the ROC curve (AUC). The study protocol was approved by the Ethics Committee of Shahid Beheshti University of Medical Sciences (ethical code: IR.SBMU.RETECH.REC.1399.010).

Participants

Outpatients with suspected COVID-19 having initial respiratory signs (including sore throat without shortness of breath), fever, cough, muscle ache, and headache were included ().

Data gathering

Pharyngeal swab samples were collected for COVID-19 test on presentation. Blood samples were collected from each participant and routine blood test including White blood cell count (WBC), Lymphocyte count (LYM), and Neutrophil count (NEU) were performed on the blood samples. Furthermore, blood biochemistry parameters such as Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), Urea, C-reactive protein (CRP), as well as Albumin and lactate dehydrogenase (LDH) were assessed using HITACHI 7600-020 automated biochemistry analyzer.

COVID-19 IgG & IgM antibody

GEN-50001-50tests 50 tests
EUR 324
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Biocredit Covid-19 Ag Detection Kit

G61RHA20 20 test cards (pkg)
EUR 95

NATtrol Zika Virus Stock (Qualitative) (1 mL)

TEST 1 mL
EUR 1106.64
Description: Please contact Gentaur in order to receive the datasheet of the product.

Purified recombinant COVID-19 (isolate Wuhan-Hu-1) NP protein

nCoVNP-126V 100ug
EUR 792
Description: Purified recombinant COVID-19(isolate Wuhan-Hu-1) NP protein was expressed in HEK293 cells.

Recombinant COVID-19 (isolate Wuhan-Hu-1) S(ΔTM) protein

nCoVS-125V 100ug
EUR 792
Description: Purified recombinant COVID-19(isolate Wuhan-Hu-1) S(ΔTM) protein was expressed in HEK293 cells.

Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit

RR-0478-02 25 tests/kit
EUR 991
Description: Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems.

Clamp set for H3760 series

H3760-CS 1 PC
EUR 140.4

Optional Temperature Probe (H3760 Series)

H3760-TP 1 PC
EUR 127.64

ProMag 3 Series Protein G

PMG3N-1 1 ml
EUR 221.4
Description: ProMag 3 Series Protein Gsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Protein G

PMG3N-10 10 ml
EUR 929.36
Description: ProMag 3 Series Protein Gsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Protein G

PMG3N-2 2 ml
EUR 330.15
Description: ProMag 3 Series Protein Gsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Protein G

PMG3N-5 5 ml
EUR 569.4
Description: ProMag 3 Series Protein Gsuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Streptavidin Microspheres

PMS3N-1 1 ml
EUR 221.4
Description: ProMag 3 Series Streptavidin Microspheressuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Streptavidin Microspheres

PMS3N-10 10 ml
EUR 929.36
Description: ProMag 3 Series Streptavidin Microspheressuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Streptavidin Microspheres

PMS3N-2 2 ml
EUR 330.15
Description: ProMag 3 Series Streptavidin Microspheressuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series Streptavidin Microspheres

PMS3N-5 5 ml
EUR 569.4
Description: ProMag 3 Series Streptavidin Microspheressuitable for use in assay developmen. This item is supplied as suspension in water.

C-Series 1000 Analyzer Software

S02-AAH-CYT-1000 CD
EUR 271

Human IL-19(Interleukin 19) ELISA Kit

EH3268 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Rat IL-19(Interleukin 19) ELISA Kit

ER1589 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 9.8pg/ml

pair of cables for ehs1000 series

EHS1000-CABLES ea
EUR 82

anti- IL-19 antibody

FNab04233 100µg
EUR 585
Description: Antibody raised against IL-19

anti- IL-19 antibody

FNab04234 100µg
EUR 585
Description: Antibody raised against IL-19

anti- IL-19 antibody

FNab04235 100µg
EUR 585
Description: Antibody raised against IL-19

anti- ARPP-19 antibody

FNab00606 100µg
EUR 505.25
Description: Antibody raised against ARPP-19

anti- Cytokeratin 19 antibody

FNab02207 100µg
EUR 548.75
Description: Antibody raised against Cytokeratin 19

anti- Cytokeratin 19 antibody

FNab02208 100µg
EUR 505.25
Description: Antibody raised against Cytokeratin 19

anti- Cytokeratin 19 antibody

FNab02209 100µg
EUR 505.25
Description: Antibody raised against Cytokeratin 19

Recombinant human Interleukin-19

P1354 100ug Ask for price
Description: Recombinant protein for human Interleukin-19

Novel Coronavirus COVID-19 (2019-nCoV) Real Time Multiplex RT-PCR Kit (Detection for 3 Genes )

RR-0479-02 25 tests/kit
EUR 1347
Description: Novel Coronavirus (2019-nCoV) Real Time Multiplex RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems. It detects N gene, E gene and RdRp gene of 2019-nCoV. RR-0479-02 has been also approverd by CFDA for emergency use and is WHO standard.

Optional Rod for Hotplate/Stirrer (H3760 Series)

H3760-ROD 1 PC
EUR 155.48

ProMag 3 Series COOH Surfactant-Free Microspheres

PMC3N-25 25 ml
EUR 807.56
Description: ProMag 3 Series COOH Surfactant-Free Microspheressuitable for use in assay developmen. This item is supplied as suspension in water.

ProMag 3 Series COOH Surfactant-Free Microspheres

PMC3N-5 5 ml
EUR 193.13
Description: ProMag 3 Series COOH Surfactant-Free Microspheressuitable for use in assay developmen. This item is supplied as suspension in water.

C-Series Mouse Inflammation Array Analysis Software

S02-AAM-INF-1 CD
EUR 271

anti- Cytokeratin 19-specific antibody

FNab02210 100µg
EUR 585
Description: Antibody raised against Cytokeratin 19-specific

DNASE TEST AGAR

D04-101-10kg 10 kg Ask for price

DNASE TEST AGAR

D04-101-2Kg 2 Kg Ask for price

DNASE TEST AGAR

D04-101-500g 500 g Ask for price

DERMATOPHYTE TEST AGAR

D04-107-10kg 10 kg
EUR 849

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